Katherine Halloran
Last Revised: Jan 24th, 2025
Professional Biography
RESEARCH INTERESTS
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Reproductive physiology and endocrinology
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Uterine, placental, and ovarian biology
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Fetal programming and developmental origins of disease
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Metabolism and environmental exposures
PROFESSIONAL EXPERIENCE
2025-Present Assistant Professor
Department of Animal and Food Sciences
University of Kentucky, Lexington, KY
2022-2024 Postdoctoral Research Fellow
Department of Pediatrics – Endocrinology
University of Michigan, Ann Arbor, MI
PUBLICATIONS
Sah N, Stenhouse C, Halloran KM, Moses RM, Newton MG, Seo H, Cain JW, Johnson GA, Wu G, Bazer FW. Effect of gestational age and fetal sex on metabolism of creatine by uteri, placentae, and fetuses of pigs. 2025. https://doi.org/10.1093/biolre/ioaf015
Halloran KM*, Zhou Y*, Bellingham M, Lea RG, Evans NP, Sinclair KD, Smith P, Padmanabhan V. Developmental programming: Impact of exposure to a real-life environmental chemical mixture via biosolids on ovarian follicle populations and AMH in sheep. 2024. Doi: 10.1093/biolre/ioae166.
Stenhouse C, Halloran KM, Hoskins EC, Moses RM, Wu G, Seo H, Johnson GA, Suva LJ, Gaddy D, Bazer FW. Progesterone regulates tissue non-specific alkaline phosphatase (TNSALP) expression and activity in ovine utero-placental tissues. 2024. doi: 0.1186/s40104-024-01048-x
Halloran KM, Saadat N, Pallas B, Vyas AK, Sargis R, Padmanabhan V. Developmental programming: Testosterone excess masculinizes female pancreatic transcriptome and function in sheep. 2024. doi: 10.1016/j.mce.2024.112234
Moses RM, Stenhouse C, Halloran KM, Sah N, Newton MG, Hoskins EC, Washburn SE, Johnson GA, Wu G, Bazer FW. Metabolic pathways of glucose and fructose II: Spatiotemporal expression of genes involved in synthesis and transport of lactate in ovine conceptuses. 2024. doi: 10.1093/biolre/ioae047
Moses RM, Stenhouse C, Halloran KM, Sah N, Hoskins EC, Washburn SE, Johnson GA, Wu G, Bazer FW. Metabolic pathways for glucose and fructose I: Synthesis and metabolism of fructose by ovine conceptuses. 2024. doi: 10.1093/biolre/ioae043
Stenhouse C, Halloran KM, Newton MG, Moses RM, Sah N, Suva LJ, Gaddy D, Bazer FW. Characterization of TNSALP expression, localization, and activity in ovine utero-placental tissues. 2023. doi: 10.1093/biolre/ioad113
Rubin JM, Pinter SZ, Halloran KM, Pallas BD, Fowlkes JB, Vyas AK, Padmanabhan V, Kripfgans O. Placental assessment using spectral analysis of the envelope of umbilical venous doppler waveforms in sheep. 2023. doi: 10.1016/j.placenta.2023.08.072
Newton MG, Stenhouse C, Halloran KM, Sah N, Moses RM, He W, Wu G, Bazer FW. Regulation of the synthesis of polyamines by progesterone, estradiol, and their receptors in the uteri of cyclic ewes. 2023. doi: 10.1093/biolre/ioad073
Sah N, Stenhouse C, Halloran KM, Moses RM, Seo H, Burghardt RC, Johnson GA, Wu G, Bazer FW. Creatine metabolism at the uterine-placental interface throughout gestation in sheep. Biology of Reproduction. 2023. doi: 10.1093/biolre/ioad052.
Stenhouse C, Newton MN, Halloran KM, Moses RM, Sah N, Suva LJ, Bazer FW. Phosphate, calcium, and vitamin D signaling, transport, and metabolism in the endometria of cyclic ewes. Journal of Animal Science and Biotechnology. 2023. doi: 10.1186/s40104-022-00803-2.
Thangaraj SV, Kachman M, Halloran KM, Sinclair K, Lea R, Bellingham M, Evans N, Padmanabhan V. Developmental Programming: Preconceptional and gestational exposure of sheep to a real-life environmental chemical mixture alters maternal metabolome in a fetal sex-specific manner. Science of the Total Environment. 2023. doi: 10.1016/j.scitotenv.2022.161054.
Halloran KM, Stenhouse C, Moses RM, Kramer AC, Sah N, Seo H, Lamarre SG, Johnson GA, Wu G, Bazer FW. The ovine conceptus utilizes extracellular serine, glucose, and fructose to generate formate via the one carbon metabolism pathway. Amino Acids. 2023. doi: 10.1007/s00726-022-03212-x.
Sah N, Stenhouse C, Halloran KM, Moses RM, Seo H, Burghardt RC, Johnson GA, Wu G, and Bazer FW. Creatine metabolism at the uterine-conceptus interface during early gestation in sheep. Biology of Reproduction. 2022. doi: 10.1093/biolre/ioac171.
Sah N, Stenhouse C, Halloran KM, Moses RM, Seo H, Johnson GA, Wu G, Burghardt RC, Bazer FW. Inhibition of SHMT2 mRNA translation increases embryonic mortality in sheep. Biology of Reproduction. 2022. doi: 10.1093/biolre/ioac152.
Moses RM, Halloran KM, Stenhouse C, Sah N, Kramer AC, McLendon B, Seo H, Wu G, Johnson GA, Bazer FW. Ovine conceptuses metabolize fructose for metabolic support during the peri-implantation period of pregnancy. Biology of Reproduction. 2022. doi: 10.1093/biolre/ioac144.
Stenhouse C, Halloran KM, Tanner AR, Suva LJ, Rozance PJ, Anthony RV, Bazer FW. Uptake of phosphate, calcium, and vitamin D by the pregnant uterus of sheep in late gestation: regulation by chorionic somatomammotropin hormone. International Journal of Molecular Sciences. 2022. doi: 10.3390/ijms23147795.
Stenhouse C, Halloran KM, Hoskins EC, Newton MG, Seo H, Dunlap KA, Satterfield MC, Johnson GA, Wu G, Gaddy D, Suva LJ, Bazer FW. Effects of exogenous progesterone on the expression of mineral regulatory molecules by ovine endometrium and placentomes. Biology of Reproduction. 2022. doi.org/10.1093/biolre/ioac042.
Stenhouse C, Halloran KM, Robyn RM, Seo H, Gaddy D, Johnson GA, Wu G, Suva LJ, Bazer FW. Effects of progesterone and interferon tau on ovine maternal-conceptus interface phosphate, calcium, and vitamin D signaling. Biology of Reproduction. 2022. doi.org/10.1093/biolre/ioac027.
Halloran KM, Stenhouse C, Moses RM, Seo H, Johnson GA, Wu G, Bazer FW. Progesterone and interferon tau regulate expression of polyamine enzymes during the ovine peri-implantation period. Biology of Reproduction. 2022. doi.org/10.1093/biolre/ioac022.
Stenhouse C, Halloran KM, Newton MG, Gaddy D, Suva LJ, Bazer FW. Novel mineral regulatory pathways in ovine pregnancy II. Calcium binding proteins, calcium transporters, and vitamin D signaling. Biology of Reproduction. 2021. doi: 10.1093/biolre/ioab063.
Stenhouse C, Halloran KM, Newton MG, Gaddy D, Suva LJ, Bazer FW. Novel mineral pathways in ovine pregnancy I. Phosphate, klotho signaling, and sodium dependent phosphate transporters. Biology of Reproduction. 2021. doi: 10.1093/biolre/ioab028.
Halloran KM, Hoskins EC, Stenhouse C, Moses RM, Dunlap KA, Satterfield MC, Seo H, Johnson GA, Wu G, Bazer FW. Pre-implantation exogenous progesterone and pregnancy in sheep II. Effects on nutrient transport in late pregnancy. Journal of Animal Science and Biotechnology. 2021. doi: 10.1186/s40104-021-00567-1.
Hoskins EC, Halloran KM, Stenhouse C, Moses RM, Dunlap KA, Satterfield MC, Seo H, Johnson GA, Wu G, Bazer FW. Pre-Implantation exogenous progesterone and pregnancy in sheep I. Polyamines, nutrient transport, and progestamedins. Journal of Animal Science and Biotechnology. 2021. doi: 10.1186/s40104-021-00554-6.
Halloran KM, Stenhouse C, Wu G, Bazer FW. Arginine, agmatine, and polyamines: Key regulators of conceptus development in mammals. Advances in Experimental Medicine and Biology. 2021. doi: 10.1007/978-3-030-74180-8_6.
Goodwine E, Rosov A, Alon T, Stenhouse C, Halloran KM, Wu G, Bazer FW. Effect of supplementation of unprotected or protected arginine to prolific ewes on maternal amino acids profile, lamb survival at birth and pre- and post-weaning lamb growth. Journal of Animal Science. 2020. 1-9. doi: 10.1093/jas/skaa284.
PROFESSIONAL MEMBERSHIPS
2022 – Present. Endocrine Society
2022 – Present. U.S. DoHAD Society
2021 – Present. American Society of Animal Science
2016 – Present. Society for the Study of Reproduction
2020 – 2022. Texas A&M Women in Science and Engineering
2016 – 2022. Texas A&M Animal Science Graduate Student Association
2016 – 2022. Texas A&M Interdisciplinary Faculty of Reproductive Biology
GRANTS, AWARDS, AND SCHOLARSHIPS
2024 – Michigan Nutrition Obesity Research Center Pilot/Feasibility Grants, University of Michigan: Funded June 2024, $50,000. “Developmental origin of MASLD in a sheep model of polycystic ovary syndrome and impact of postnatal obesity on its severity.” Role: PI
2023 – Early Career Forum, Endocrine Society ($430 complimentary registration + $400 travel award)
2023 – 2025 – Environmental Toxicology and Epidemiology Training Grant, NIH Award Number T32ES007062, School of Public Health, University of Michigan
2022 – American Society of Animal Science, Wettemann Graduate Scholar in Physiology Award ($1000)
2022 – Texas A&M Department of Animal Science Travel Award ($500)
2022 – Texas A&M Department of Animal Science, A.M. “Tony” Sorensen, Jr. Achievement Award ($1,000)
2021 – Texas A&M Department of Animal Science, Outstanding PhD Award
2021 – Texas A&M Animal Science Graduate Student Association, ASGSA Scholarship ($250)
2019 – Texas A&M Department of Animal Science, Sorensen Physiology of Reproduction Travel Award ($500)
2018 – Texas A&M Department of Animal Science, Sorensen Physiology of Reproduction Travel Award ($500)
2018 – Texas A&M Animal Science Graduate Student Association ASGSA Scholarship ($100)
2018 – Society for the Study of Reproduction, Larry Ewing Memorial Trainee Travel Fund ($100)
2017 – Society for the Study of Reproduction, Larry Ewing Memorial Trainee Travel Fund ($100)
2011-2013 – California Polytechnic State University San Luis Obispo, Department of Animal Science, Boyle-McOmie Scholarship ($6,000)
INVITED ORAL PRESENTATIONS
American Society for Animal Science, June 2022. (Oklahoma City, Oklahoma, USA)
Interdisciplinary Faculty of Reproductive Biology Texas A&M University, December 2020 (Virtual)